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MIDI "mute"?

I'm looking for a way to mute the output of my drum machine (an Alesis 
SR-16) via MIDI.  
Currently my Echoplex is slaved to the SR-16.  Sometimes I want to mute 
the drum machine without decoupling it from the Echoplex, so that when I 
bring the drums back in, everything's still in sync.  My audio mixer 
doesn't have channel mute, and I'm looking for a way to do this with a 
Anyone have any suggestions?